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Osteopontin Recombinant Protein

Osteopontin Recombinant Protein

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Disponibilidad: Bajo pedido

0.01  (Excluded VAT) Tamaño: 0.01 mg

Osteopontin Recombinant Protein
Osteopontin Recombinant Protein

Catalog number: / Tamaño: / Precio: EUR (Excluded VAT)

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Osteopontin Recombinant Protein
Osteopontin Recombinant Protein

Catalog number: / Tamaño: / Precio: EUR (Excluding VAT)

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Proveedor: Gentaur
Disponibilidad: En orden
Número del catálogo: 223-40-122-001mg
Descripción
Osteopontin is a secreted glycoprotein that functions as a ligand to alphavbeta3 integrin and possibly other receptors. It binds tightly to hydroxyapatite and can act as a structural component of the extracellular mineralized matrix. Osteopontin is initially secreted as a 298 amino acid protein, which is subject to multiple post-translational modifications including glycosylation, phosphorylation, and specific proteolytic cleavages into various smaller molecular weight fragments. Osteopontin is expressed in a wide range of cells and tissues including osteoblasts, various tumor cell lines, extraosseous cells in the inner ear, brain, kidney, deciduum, placenta and odontoblasts. In addition to its involvement in mineralized matrix formation, Osteopontin can also function as a cytokine that stimulates the release of IFNγ and IL-12, while inhibiting the production of IL-10. Recombinant human Osteopontin is a 298 amino acid protein, which, due to glycosylation, migrates at an apparent molecular weight of 60.0-65.0 kDa by SDS-PAGE analysis under reducing conditions.
Especificaciones
  • Tested Applications: N/A
  • Applications: N/A
  • Predicted Molecular Weight: N/A
  • Physical state: Lyophilized
  • Buffer: N/A
  • Concentration: N/A
  • NCBI official symbol: SPP1
  • Accession #: NP_000573.1
  • Protein GI: 4759166
  • NCBI gene ID#: 6696
  • NCBI official full name: secreted phosphoprotein 1
  • NCBI organism: Homo sapiens
  • Peptide sequence: IPVKQADSGS SEEKQLYNKY PDAVATWLNP DPSQKQNLLA PQNAVSSEET NDFKQETLPS KSNESHDHMD DMDDEDDDDH VDSQDSIDSN DSDDVDDTDD SHQSDESHHS DESDELVTDF PTDLPATEVF TPVVPTVDTY DGRGDSVVYG LRSKSKKFRR PDIQYPDATD EDITSHMESE ELNGAYKAIP VAQDLNAPSD WDSRGKDSYE TSQLDDQSAE THSHKQSRLY KRKANDESNE HSDVIDSQEL SKVSREFHSH EFHSHEDMLV VDPKSKEEDK HLKFRISHEL DSASSEVN
  • SWISSPROT #: P10451
  • Background Reference 1: N/A
  • Background Reference 2: N/A
  • Background Reference 3: N/A
  • Background Reference 4: N/A
  • Background Reference 5: N/A
  • Source: HEK293 cells
  • Species: Human
  • By Source: Human Cells
  • By Species: Human
  • Fusion tag: N/A
  • Sequence: IPVKQADSGS SEEKQLYNKY PDAVATWLNP DPSQKQNLLA PQNAVSSEET NDFKQETLPS KSNESHDHMD DMDDEDDDDH VDSQDSIDSN DSDDVDDTDD SHQSDESHHS DESDELVTDF PTDLPATEVF TPVVPTVDTY DGRGDSVVYG LRSKSKKFRR PDIQYPDATD EDITSHMESE ELNGAYKAIP VAQDLNAPSD WDSRGKDSYE TSQLDDQSAE THSHKQSRLY KRKANDESNE HSDVIDSQEL SKVSREFHSH EFHSHEDMLV VDPKSKEEDK HLKFRISHEL DSASSEVN
  • Biology activity: Biological activity was determined by its ability to enhance cell adhesion of murine B16-F1 cells.
  • Purity: Greater than 97% by SDS-PAGE gel and HPLC analyses.
  • Endotoxin level is less than 0.1 ng per µg (1EU/µg).
Almacenamiento y envío
The lyophilized Osteopontin recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted Osteopontin is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As with any protein, exposing Osteopontin recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
Notas
This product is for research use only.
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